"Recent meta-analyses show selective serotonin reuptake inhibitors have no clinically meaningful advantage over placebo
Claims that antidepressants are more effective in more severe conditions have little evidence to support them
Methodological artefacts may account for the small degree of superiority shown over placebo
Antidepressants have not been convincingly shown to affect the long term outcome of depression or suicide rates
Given doubt about their benefits and concern about their risks, current recommendations for prescribing antidepressants should be reconsidered",
http://www.bmj.com/cgi/content/full/331/7509/155